Chlamydia trachomatis CT229 Subverts Rab GTPase-Dependent CCV Trafficking Pathways to Promote Chlamydial Infection

Chlamydia trachomatis in sexually active teenage girls. Factors related to genital chlamydial infection: a prospective study.

The incidence of new infections with C trachomatis was found to be 19%. Predisposing factors for a subsequent chlamydial infection were multiple partners, smoking and previous infection with C trachomatis. Girls with a spread cervical ectopy were not more likely to contract a chlamydial infection in one year than girls without an ectopy. Oral contraceptive use was not found to predispose for a ...

Infection Modulates Chlamydia trachomatis

P-59: Chlamydia Trachomatis Infection in Femaleswith Secondary Infertility

Background: We designed a prospective study to assess the role of Chlamydia in secondary infertility Materials and Methods: 40 women with secondary infertility and 30 term healthy pregnant women of similar age composition were studied for past and present chlamydia trachomatis infection. Women attending the outpatient department of Obstetrics and Gynaecology with complaint of secondary infertil...

Immunology of Non-Trachomatis Chlamydial Infection

halamydia are obligate intracellular parasites with co plexe reproductive cycle. The genus comprises four different species: C. trachomatis, C. pneumoniae, C. psittaci and C. pecorum. Most of the work concerning the immune response is found on C. trachomatis as it is a major public health problem throughout the world. However the other species are also of interest as C. psittaci is one of the m...

Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion

The Rab GTPase effector, Rab-coupling protein (RCP) is known to promote invasive behaviour in vitro by controlling integrin and receptor tyrosine kinase (RTK) trafficking, but how RCP influences metastasis in vivo is unclear. Here we identify an RTK of the Eph family, EphA2, to be a cargo of an RCP-regulated endocytic pathway which controls cell:cell repulsion and metastasis in vivo. Phosphoryl...